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Oral Weight Loss Medications
When used in combination with our medical weight loss programs, FDA-approved weight loss medications including phentermine, tenuate (diethylpropion), Contrave and Qsymia can be helpful not only with increasing both speed and amount of weight loss, but also with reducing the sensation of hunger. Weight loss medications are not a substitute for a good diet and exercise program – they are designed to complement the behavioral program.
Looking for the “Ozempic Effect” in a Pill?
We now offer Oral Wegovy® (Semaglutide)—the first FDA-approved oral GLP-1 for weight loss. Experience powerful results without the needles.
Oral Weight Loss Medications & Appetite Suppressants in Denver
While injectable medications like Zepbound® and Wegovy® dominate the headlines, they aren’t the right fit for everyone. At Clinical Nutrition Center, we offer a complete pharmacy of oral weight loss solutions. Whether you are looking for a lower-cost alternative or a daily stimulant to curb hunger, our physician-led team can help you find the right tool.
Stimulant Appetite Suppressants
These medications work by stimulating the hypothalamus to release norepinephrine, reducing hunger and increasing satiety. They are often the most affordable option for patients paying out-of-pocket.
Phentermine (Adipex-P®)
Best For: Reducing hunger and boosting energy.
Phentermine is the most commonly prescribed weight loss medication in the US. It is a cost-effective tool to help control appetite while you implement dietary changes.
Tenuate® (Diethylpropion)
Best For: Patients sensitive to stronger stimulants.
While the brand name “Tenuate” has been discontinued in retail pharmacies, CNC dispenses this medication directly from our office. Many patients find Tenuate causes less jitters/insomnia than phentermine while effectively curbing evening cravings.
Combination Oral Therapies
These modern oral medications target multiple pathways in the brain (including the reward system) to reduce not just hunger, but also cravings and emotional eating.
Contrave® (Bupropion + Naltrexone)
Contrave combines an antidepressant (Wellbutrin) with an opioid blocker (Naltrexone) to target the brain’s “craving center.” It is excellent for patients who struggle with emotional eating or intense sugar cravings.
- Cost: Approx $99 – $130 per month.
- Availability: We can prescribe this to the manufacturer’s pharmacy ($99 mail order) or dispense it immediately at our clinic (~$130) for your convenience.
Qsymia® (Phentermine + Topiramate)
Qsymia combines the appetite suppression of phentermine with topiramate, a medication that increases satiety (fullness). Clinical trials show it produces the highest weight loss of any oral medication (around 10%).
Cost is approximately $98/month through the Qsymia Engage home delivery program.
Comparison: Oral Meds vs. Injectables
| Medication | Mechanism | Est. Cost | Availability |
|---|---|---|---|
| Phentermine / Tenuate | Stimulant / Appetite Suppression | $ (Low) | In-Office Dispensing |
| Contrave® | Cravings & Reward Control | $99 – $130 | Mail Order or In-Office |
| Oral Wegovy® | GLP-1 (Satiety & Metabolic) | $149 Start | Prescription / In-Office |
| Zepbound® / Wegovy® | Injection (GLP-1) | $$ (Varies) | Pharmacies |
Which Pill is Right For You?
Stop guessing. Our board-certified providers will review your medical history and biology to select the safest, most effective option.
Weight Loss Medications
| Cost | $25 – $50 / month |
| Average Weight Loss | ~8-10% 25 pounds |
| Avoid if… | Heart disease, stroke, uncontrolled hypertension, uncontrolled seizure |
| Side Effects | Elevation of blood pressure or heart rate, agitation, insomnia, dry mouth |
| Other Benefits | Improved energy and focus |
| Cost | $25 – $150 / month |
| Average Weight Loss | ~8-10% 25 pounds |
| Avoid if… | Heart disease, stroke, uncontrolled hypertension, uncontrolled seizure |
| Side Effects | Elevation of blood pressure or heart rate, agitation, insomnia, dry mouth |
| Other Benefits | Improved energy and focus, less stimulation than phentermine, improved mood |
| Cost | $99 – $130 / month |
| Average Weight Loss | ~8% 25 pounds |
| Avoid if… | Seizure history, opioid pain medications |
| Side Effects | Nausea, constipation, headache, insomnia |
| Other Benefits | Improved mood, decreased cravings |
| Cost | $98 / month |
| Average Weight Loss | ~10-12% 25 pounds |
| Avoid if… | Heart disease, stroke, uncontrolled hypertension, uncontrolled seizure, kidney stones, unsafe in pregnancy |
| Side Effects | Elevation of blood pressure or heart rate, agitation, insomnia, dry mouth, confusion, word recall |
| Other Benefits | Improved energy and focus, less migraine headaches |
Are you ready to learn more?
The first visit is free. What do you have to lose?
*Weight Loss medications are not appropriate for all individuals and will be prescribed only if deemed an appropriate treatment option by Dr. Lazarus, Heather Thomas, PA-C or Jamie Shriver, PA-C. The purchase of prescription medications from us is completely optional – programs do not include the cost of medication. We stock many medications, but you are welcome to request a written prescription or have our providers e-prescribe to the pharmacy of your choice.